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Shedding light on skin cancer.
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Porphyria cutanea tarda (PCT) is the most frequent type of porphyria worldwide and results from a catalytic deficiency of uroporphyrinogen decarboxylase (UROD), the fifth enzyme in heme biosynthesis. At least two different types of PCT are currently distinguished: an acquired variant, also referred to as sporadic or type I PCT, in which the enzymatic deficiency is limited to the liver; and an a...
متن کاملContext and Mythology
In this thesis, I will survey some philosophically representative approaches to the problem of the relationship between context and meaning. Starting from G.W.F. Hegel’s discussion of the meaninglessness of indexical terms in the Phenomenology of Spirit, I will investigate Gottlob Frege’s notion of context and the legacy of this notion in the formal sciences of language, showing that this appro...
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The study by Stefanadis et al. in this issue indicates that treatment with a variety of statins reduces the release of heat from atherosclerotic plaques in the human coronary artery. This observation suggests that statins exert a beneficial effect on the inflammatory process that exists in the vascular wall in a variety of acute coronary syndromes. The finding that this effect was most pronounc...
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ژورنال
عنوان ژورنال: Nature
سال: 2012
ISSN: 0028-0836,1476-4687
DOI: 10.1038/491527e